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Skripsi farmasi dengan judul ” SINTESIS N�-BENZILIDENISONIAZIDA DAN N�-(Four-HIDROKSI-Three-METOKSI BENZILIDEN) ISONIAZIDA DENGAN METODE IRADIASI GELOMBANG MIKRO Repository c” berikut bisa Kamu unduh disini, dan masih banyak skripsi terupdate lainnya.

TITA ALVINDA KOSASIH, 051111107

(2016)

SINTESIS N�-BENZILIDENISONIAZIDA DAN N�-(Four-HIDROKSI-Three-METOKSI BENZILIDEN) ISONIAZIDA DENGAN METODE IRADIASI GELOMBANG MIKRO.

Skripsi thesis, UNIVERSITAS AIRLANGGA.

Summary

The goal of this research was to synthesize N’-(Four-hydroxy-Three-
methoxybenzylidene)isoniazide utilizing microwave irradiation technique.
The goal compound was synthesized by reacting vanilline with
isoniazide (2:1). Purity check was accomplished by skinny layer chromatography
(TLC) and melting level.
As a comparability, N’-benzylideneisoniazide was synthesized
by reacting benzaldehyde with isoniazide (2:1) to show that
vanilline (Four-hydroxy-Three-methoxybenzaldehyde) is extra reactive than
benzaldehyde in response with isoniazide. Identifications of
synthesized compound (product) have been confirmed by UV-VIS, FT-IR
and 1H-NMR spectroscopy. Share yield of N’-(Four-hydroxy-Three-
methoxybenzylidene)isoniazide and N’-benzylideneisoniazide have been
82 % and 77 %, respectively.

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