Skripsi farmasi yang berjudul ” STUDI PENGGUNAAN EPOETIN ALFA DAN EPOETIN BETA PADA PASIEN PENYAKIT GINJAL KRONIK YANG MENJALANI HEMODIALISIS (Riset dilakukan di Instalasi Hemodialisis RSUD Dr. Soetomo Surabaya Repository c” berikut bisa Kamu download disini, dan masih banyak skripsi terupdate lainnya.
DEASY MAFAZADARA, 051111215
STUDI PENGGUNAAN EPOETIN ALFA
DAN EPOETIN BETA PADA PASIEN PENYAKIT GINJAL KRONIK YANG MENJALANI HEMODIALISIS
(Riset dilakukan di Instalasi Hemodialisis
RSUD Dr. Soetomo Surabaya.
Skripsi thesis, UNIVERSITAS AIRLANGGA.
BACKGROUND: Erythropoietin (EPO) is a glycoprotein hormone which controls manufacturing of purple blood cell precursor. The lower of EPO is the primary reason for anemia in sufferers with persistent kidney illness (CKD). Erythropoiesis stimulating brokers (ESAs) remedy is step one in dealing with anemia in sufferers with CKD to substitute the shortage of erythropoietin. There are a number of recombinant human EPO as epoetin alpha and beta. Throughout the remedy, there are some elements influencing the method of erythropoesis and the efficacy of EPO remedy together with uremic situation, infection-inflamation, oedema, and Ca x P stage.
OBJECTIVE: The goal of the research was to explain using epoetin alpha and beta together with the sort, dose, route, influencing issue of EPO efficacy and chance of drug associated drawback (DRP).
SUBJECTS AND METHODS: It was an observational research carried out in Hemodialysis Set up of Dr. Soetomo Educating Hospital Surabaya throughout March to Could 2015. The research has been authorized by ethic committee. Standards of inclusions of subjek had been affected person who underwent remedy of epoetin alpha or beta, with information of Hb, SI, TIBC, Ca x P, BUN, leukocytes, weight, blood stress, physique temperature, and vascular entry.
RESULTS: Whole pattern obtained on this research had been 27 sufferers. The kind of epoetin used had been epoetin alpha (51,85%), and epoetin beta (48,15%). The dose of epoetin alpha and beta obtained by sufferers had been 3000 IU and 2000 IU respectively with out calculating dose individually. All sufferers obtained underdose of epoetin alpha and beta. The route of remedy had been SC (96,30%), and IV (three.70%). From this research, it could possibly be noticed that sufferers with excessive uremic situation had low common of Hb. Evaluation of things that affecting Hb embody uremia circumstances, ranges of Ca x P, and edema cannot be analyzed as a result of the info much less consultant. Uncomfortable side effects that is likely to be occurred in the course of the remedy had been headache and cough.
|Extra Data:||KKB KK-2 FF FK.44/15 Maf s|
|Uncontrolled Key phrases:||Erythropoietin, anemia, persistent kidney illness|
|Topics:||R Medicine > RS Pharmacy and materia medica|
|Divisions:||05. Fakultas Farmasi > Farmasi Klinis|
|Date Deposited:||02 Apr 2016 14:22|
|Final Modified:||02 Apr 2016 14:22|
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