download tesis FARMASI lengkap
download tesis FARMASI lengkap

Tesis farmasi dengan judul ” ANALISIS PENGGUNAAN METILDOPA TERHADAP PERUBAHAN RASIO FAKTOR ANGIOGENIK (sFlt-1/ PIGF) PADA PASIEN PREEKLAMPSIA BERAT (PEB) (Riset dilakukan di Ruang Bersalin dan Rawat Inap Kandungan dan Kebidanan RSU Haji Surabaya) Repository c” berikut bisa Kamu unduh disini, dan masih banyak skripsi terupdate lainnya.

Moch Rizal Ardiansyah, 051515153029

(2017)

ANALISIS PENGGUNAAN METILDOPA TERHADAP PERUBAHAN RASIO FAKTOR ANGIOGENIK (sFlt-1/ PIGF) PADA PASIEN PREEKLAMPSIA BERAT (PEB) (Riset dilakukan di Ruang Bersalin dan Rawat Inap Kandungan dan Kebidanan RSU Haji Surabaya).

Thesis thesis, UNIVERSITAS AIRLANGGA.

Summary

Background – An imbalance in circulating angiogenic components play a central position within the
pathogenesis of preeclampsia. Over the previous decade, quite a few research confirmed that prime
sFlt-1 and low PIGF are current throughout preeclampsia girls. As well as, elevated plasma
sFlt-1 and decreased PIGF have been confirmed to correlate with preeclampsia phenotypes.
Utilizing angiogenic issue of the sFlt-1/ PIGF ratio for diagnostic and prognostic exams in
preeclampsia is best than utilizing single marker of angiogenic issue. Methyldopa is the
first-line drug for hypertension in being pregnant, it’s believed to decrease blood strain by
direct mechanism on á2-adrenoreceptors. A examine demonstrated the power of methyldopa
to considerably lower sFlt-1 degree in extreme preeclampsia girls.
Goal – The purpose of this examine was to investigate the impact of methyldopa on angiogenic
issue of the sFlt-1/ PIGF ratio in extreme preeclampsia girls.
Strategies – This examine was a potential examine with time restricted sampling, throughout June to
October 2017 interval. The protocol of this examine was accredited by moral committee of Haji
Educating Hospital Surabaya. The Serum ranges of sFlt-1 and PIGF have been measured earlier than
and after methyldopa remedy, utilizing 250-500 mg for Zero-24 hours (earlier than childbirth). sFlt-1/
PIGF ratio have been calculated from sFlt-1 and PIGF ranges. Immunoassay methodology was used to
analyze the serum ranges of sFlt-1 and PIGF biomarkers earlier than and after methyldopa
remedy.
Outcome – 11 sufferers have been included on this examine. The outcomes confirmed that the imply serum
ranges of sFlt-1/ PIGF ratio have been 8147.08 ± 23185.47 pg/ mL earlier than remedy and 453.17 ±
624.9 pg/ mL after methyldopa remedy. The imply serum ranges of sFlt-1/ PIGF ratio
between earlier than and after remedy decreased 7693.91 pg/ mL (p > Zero.05). All of sufferers
have been grouped in three group primarily based on whole dose of methyldopa used, i.e 1500, 750 and 500
mg, whereas the share of the lower in sFlt-1/ PIGF ratio at every group have been 97.16 %
(p>Zero.05), 93.04% (p>Zero.05), and 21.27% (p>Zero.05), respectively.
Conclusion – There was a lowering development in sFlt-1/ PIGF ratio after methyldopa remedy
in extreme preeclampsia.

Merchandise Sort: Thesis

(Thesis)

Further Info: KKB KK-2 TFK. 12-18 Ard a
Uncontrolled Key phrases: methyldopa, extreme preeclampsia, sFlt-1/ PIGF ratio, angiogenic components, sFlt-1, PIGF
Topics: R Medicine > RG Gynecology and obstetrics > RG1-991 Gynecology and obstetrics
Divisions: 05. Fakultas Farmasi > Farmasi Klinis
Creators:
Creators E-mail
Moch Rizal Ardiansyah, 051515153029 UNSPECIFIED
Contributors:
Contribution Identify E-mail
Contributor Yulistiani, Dr., M.Si., Apt UNSPECIFIED
Contributor Eddy Zarkaty, dr., Sp.OG UNSPECIFIED
Depositing Person:

Tatik Poedjijarti

Date Deposited: 11 Mar 2018 18:35
Final Modified: 11 Mar 2018 18:35
URI: http://repository.unair.ac.id/id/eprint/70569
Sosial Share:

Actions (login required)

View Item View Merchandise

Demikianlah skripsi terkait ” ANALISIS PENGGUNAAN METILDOPA TERHADAP PERUBAHAN RASIO FAKTOR ANGIOGENIK (sFlt-1/ PIGF) PADA PASIEN PREEKLAMPSIA BERAT (PEB) (Riset dilakukan di Ruang Bersalin dan Rawat Inap Kandungan dan Kebidanan RSU Haji Surabaya) Repository ” ini. Harus kamu tahu skripsi ini asalnya dari situs eksternal

Silahkan ke URL ini untuk melakukan download

DOWNLOAD

Tinggalkan Balasan

Alamat email Anda tidak akan dipublikasikan. Ruas yang wajib ditandai *