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Tesis farmasi yang berjudul ” PENGARUH SUPLEMENTASI PROBIOTIK DAN VITAMIN B1, B6, B12 TERHADAP PERUBAHAN KADAR IFN-γ DAN IL-6 PADA PASIEN TUBERKULOSIS DENGAN OBAT ANTI TUBERKULOSIS KATEGORI 1 (Studi di KSM Pulmonologi & Ilmu Kedokteran Respirasi RS UNAIR Surabaya serta Puskesmas di Lingkungan Dinas Kesehatan Kota Surabaya) Repository c” ini bisa Kamu unduh disini, dan masih banyak skripsi ter-baru lainnya.

Lintang Bismantara G.P.S. S. Farm., Apt., 051315153027

(2017)

PENGARUH SUPLEMENTASI PROBIOTIK DAN VITAMIN B1, B6, B12
TERHADAP PERUBAHAN KADAR IFN-γ DAN IL-6 PADA PASIEN TUBERKULOSIS DENGAN OBAT ANTI TUBERKULOSIS KATEGORI 1
(Studi di KSM Pulmonologi & Ilmu Kedokteran Respirasi RS UNAIR Surabaya serta Puskesmas di Lingkungan Dinas Kesehatan Kota Surabaya).

Thesis thesis, Universitas Airlangga.

Summary

ABSTRACT
Background : The supplementation of probiotics and vitamin B1, B6, B12 had been proven
to supply advantages for enhancing the immune system throughout respiratory infections, corresponding to
pneumonia and TB. The cytokines are a part of immune system that capabilities because the TB
pathomechanism, IFN-γ and IL-6 are cytokines which have native and systemic results to
remove tuberculosis micro organism.
Aims : To analyse the impact of probiotics and vitamin B1, B6 and B12 supplementation
on plasma ranges of IFN-γ and IL-6 in TB sufferers with first line oral antituberculosis.
Methodology : This examine was an observational, pre-post take a look at randomised management inside
November 2016 till January 2017 and it had been reviewed by the Ethics Committee of Dr
Soetomo Instructing Hospital. Plasma ranges had been decided by ELISA methodology. Blood
samples had been taken as a lot as 3 times earlier than remedy, after a month and two months.
Outcome : There have been 22 samples which had been divided into the management group (11 samples) and
the remedy group with supplementations (11 samples). Sufferers attribute had been
homogeneous between each teams. After a month statement, the imply degree of IFN-γ
elevated in each teams (p = zero.18) then decreased dramatically particularly in remedy group
(p = zero.01). The imply ranges of IL-6 in the course of the examine development to decreased in each teams such
as after a month within the management group (p = zero.02) and remedy group (p = zero.04).
Conclusion : The imply degree of IFN-γ was elevated better, and declining development of IL-6
had been decrease in sufferers utilizing supplementation after a month.

Merchandise Kind: Thesis

(Thesis)

Extra Info: KKB KK-2 TFK.03/18 Dju a
Uncontrolled Key phrases: IFN-γ, IL-6, oral antituberculosis, probiotics, supplementation in TB affected person,tuberculosis, vitamin B
Topics: R Medicine > RS Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi > Farmasi Klinis
Creators:
Creators E-mail
Lintang Bismantara G.P.S. S. Farm., Apt., 051315153027 UNSPECIFIED
Contributors:
Contribution Identify E-mail
Contributor Didik Hasmono, Drs. , MS., Apt UNSPECIFIED
Contributor Abdulloh Machin, dr., Sp.S UNSPECIFIED
Depositing Consumer:

sugiati

Date Deposited: 08 Mar 2018 16:43
Final Modified: 08 Mar 2018 16:43
URI: http://repository.unair.ac.id/id/eprint/70483
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