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Tesis farmasi yang berjudul ” PERUBAHAN KADAR SST2 PADA PASIEN GAGAL JANTUNG SETELAH PEMBERIAN TERAPI KOMBINASI ACE-INHIBITORS DAN β-BLOCKERS (Riset dilaksanakan di IRNA SMF Kardiologi dan Kedokteran Vaskular RSUD Dr. Soetomo Surabaya) Repository c” berikut bisa Kamu unduh disini, dan masih banyak skripsi terupdate lainnya.

Lelly Winduhani Astuti, 051515153025

(2017)

PERUBAHAN KADAR SST2 PADA PASIEN GAGAL JANTUNG SETELAH PEMBERIAN TERAPI KOMBINASI ACE-INHIBITORS DAN β-BLOCKERS (Riset dilaksanakan di IRNA SMF Kardiologi dan Kedokteran Vaskular RSUD Dr. Soetomo Surabaya).

Thesis thesis, UNIVERSITAS AIRLANGGA.

Summary

Background: Coronary heart failure brought on by declining of coronary heart means to flow into blood, which
result in compensation mechanism. Continued compensation mechanism induce cardiac
remodelling.
sST2 is a cardiac biomarker which was expressed in mechanically stretched myocyte. sST2
has a job in myocyte fibrosis and hyperthopy, that brought about cardiac remodelling. ACE
Inhibitors and and β blockers had been beneficial for coronary heart failure, stop remodelling
utilizing a number of mechanism, certainly one of them is lessening myocardial stretch.
Goal: This examine was aimed to research the impact of ACE inhibitors and β-blockers
mixture remedy on sST2 degree, as a cardiac marker, on inpatients with coronary heart failure.
Strategies: This examine was a potential observational examine with one group pretestposttest.
17 sufferers had been collected utilizing consecutive sampling. sST2 had been measured
earlier than and after mixture remedy, after each medication attain regular state. Moral
committee of RSUD Dr. Soetomo accepted this examine. sST2 degree had been examined utilizing
ELISA, and statistically processed utilizing Wilcoxon take a look at to check sST2 pre and publish
degree.
Consequence: From 17 sufferers, lower of sST2 degree had been present in 13 sufferers. On this examine,
we discovered the vary of sST2 earlier than remedy had been 16.Eight-2772 ng/nL whereas sST2 degree after
remedy was 12.9-1299.9 ng/mL. The imply of the lower was 63.7%. sST2 degree had been
considerably lower (p=zero.zero17)
Conclusion: There was a major lower in sST2 degree pre and publish.

Merchandise Kind: Thesis

(Thesis)

Extra Info: KKB KK-2 TFK. 13-18 Ast p
Uncontrolled Key phrases: sST2, Coronary heart failure, ACE inhibitors, β-blockers
Topics: R Medicine > RC Internal medicine > RC666-701 Diseases of the circulatory (Cardiovascular) system
R Medicine > RM Therapeutics. Pharmacology
Divisions: 05. Fakultas Farmasi > Farmasi Klinis
Creators:
Creators E-mail
Lelly Winduhani Astuti, 051515153025 UNSPECIFIED
Contributors:
Contribution Identify E-mail
Contributor Suharjono, Prof. Dr., M.S., Apt. UNSPECIFIED
Contributor Muh. Aminuddin, dr., SpJP(Ok), FIHA, FASCC UNSPECIFIED
Depositing Person:

Tatik Poedjijarti

Date Deposited: 11 Mar 2018 18:09
Final Modified: 11 Mar 2018 18:09
URI: http://repository.unair.ac.id/id/eprint/70566
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